Understanding Keratoconus: Causes, Treatments, and Living with the Condition

Keratoconus is a progressive eye disorder that affects the shape and thickness of the cornea, leading to visual impairment. This article provides a comprehensive overview of keratoconus, its causes, how it alters corneal geometry, available treatments—including corneal collagen cross-linking—and strategies for managing the condition effectively.

What is Keratoconus (KC)?

Keratoconus is a degenerative condition characterized by the thinning and bulging of the cornea into a cone-like shape. The cornea is the transparent front layer of the eye responsible for focusing most of the light entering the eye. In keratoconus, the distorted corneal shape leads to blurred or distorted vision, increased sensitivity to light, and difficulties with night vision.

Causes of Keratoconus

The exact cause of keratoconus is not fully understood, but several factors are believed to contribute:

  • Genetic Predisposition: A family history of keratoconus increases the likelihood of developing the condition.
  • Environmental Factors: Chronic eye rubbing, often associated with allergies or eczema, can weaken the corneal structure.
  • Biochemical Factors: Imbalances in corneal enzymes may lead to oxidative stress, damaging collagen fibers in the cornea.
  • Systemic Conditions: Certain conditions like Down syndrome and connective tissue disorders are associated with a higher risk.

Corneal Geometries in Keratoconus

In a healthy eye, the cornea has a smooth, dome-like shape that focuses light precisely onto the retina. Keratoconus disrupts this geometry:

  • Thinning of the Cornea: Central or paracentral thinning weakens the corneal structure.
  • Cone-like Protrusion: The weakened area bulges outward, forming a cone shape.
  • Irregular Astigmatism: The distorted shape causes light to refract improperly, leading to blurred or distorted vision.

Monitoring Keratoconus

Early detection and regular monitoring are crucial:

  • Corneal Topography: Maps the curvature of the cornea to detect changes over time.
  • Pachymetry: Measures corneal thickness to assess progression.
  • Visual Acuity Tests: Evaluate the impact on vision and the effectiveness of corrective lenses.

Effective Treatments for Keratoconus

Treatment depends on the severity and progression of the condition.

Eyeglasses and Soft Contact Lenses

  • Purpose: Correct mild refractive errors in early stages.
  • Limitations: May become ineffective as the cornea becomes more irregular.

Specialty Contact Lenses

What are Specialty Contact Lenses?

These lenses are designed to fit the unique shape of a keratoconic cornea, providing better vision correction.

  • Rigid Gas Permeable (RGP) Lenses: Provide a smooth refractive surface over the irregular cornea.
  • Hybrid Lenses: Combine an RGP center with a soft outer skirt for comfort.
  • Scleral Lenses: Large-diameter lenses that vault over the cornea, resting on the sclera.

Are All Keratoconus Lenses Similar?

No, they vary in design and material to address different stages and severities of keratoconus. An eye care professional customizes the lens type based on individual needs.

1888: The Birth Year of Scleral Lenses

Scleral lenses were first conceptualized in 1888. Modern advancements have made them a popular choice for keratoconus due to their comfort and effectiveness in providing clear vision.

Corneal Collagen Cross-Linking (CXL)

What is Corneal Collagen Cross-Linking (CXL)?

CXL is a minimally invasive procedure aimed at strengthening the corneal tissue to halt the progression of keratoconus.

  • Procedure: Riboflavin (vitamin B2) drops are applied to the cornea, which is then exposed to ultraviolet A (UVA) light.
  • Mechanism: The interaction between riboflavin and UVA light promotes new collagen bonds, increasing corneal rigidity.

Keratoconus & CXL

CXL is most effective when performed in the early stages of keratoconus.

  • Benefits: Stabilizes the cornea, slows or stops progression, and may improve corneal shape.
  • Considerations: Not typically aimed at improving vision but preserving existing vision.

Lifespan of CXL Effects

Studies indicate that the effects of CXL are long-lasting, with many patients experiencing stability for years. Regular follow-ups are essential to monitor the cornea’s condition.

Keratoconus and Invasive Procedures

Intrastromal Corneal Ring Segments (ICRS) – Rings & Intacs

  • Purpose: Flatten and support the cornea by inserting semi-circular rings.
  • Benefits: Can improve vision and reduce astigmatism, often used in conjunction with other treatments.

When to Consider Corneal Transplantation (Keratoplasty)

A corneal transplant may be necessary when:

  • Advanced Keratoconus: Severe thinning or scarring of the cornea.
  • Contact Lens Intolerance: Unable to achieve adequate vision correction with lenses.
  • Significant Vision Loss: Impacting quality of life and daily activities.

Living a Successful Life with Keratoconus

Managing keratoconus effectively allows individuals to lead active, fulfilling lives.

  • Regular Eye Exams: Essential for monitoring and adjusting treatments.
  • Protective Measures: Avoid eye rubbing and wear UV-protective sunglasses.
  • Lifestyle Adjustments: Optimize lighting conditions and use visual aids if necessary.
  • Support Networks: Connect with support groups and counseling if needed.

Role of Eye Care Professionals

Role of Optometrists in Managing Keratoconus

  • Initial Detection: Often the first to identify keratoconus during routine exams.
  • Lens Fitting: Specialize in fitting custom contact lenses.
  • Ongoing Care: Monitor progression and coordinate with ophthalmologists.

Role of Ophthalmologists in Managing Keratoconus

  • Advanced Treatments: Perform surgical procedures like CXL and corneal transplants.
  • Medical Management: Address associated conditions and complications.
  • Collaborative Care: Work with optometrists to provide comprehensive management.

Meet Dr. Kamal: Leading Specialist in Keratoconus Care

Dr. Kamal is a distinguished optometrist specializing in the diagnosis and treatment of keratoconus. With a wealth of experience and a patient-focused approach, Dr. Kamal provides comprehensive care tailored to each individual’s needs. Utilizing the latest advancements in eye care—including corneal collagen cross-linking, specialty contact lens fittings, and personalized treatment plans—Dr. Kamal is dedicated to helping patients achieve optimal vision and improve their quality of life.


Take the Next Step Towards Better Vision

Don’t let keratoconus limit your life. Schedule a consultation with Dr. Kamal today to explore personalized treatment options for managing keratoconus.